In order to comply with brand requirements and government regulations, suppliers of textile and leather products must be able to identify the potential negative impacts their chemical processes may have on the environment, workers’ health, and consumer safety. It can be a difficult and confusing task to quantify these impacts – especially for suppliers that “finish” textile and leather products and may not receive complete chemical information from their own suppliers. This guidance document is intended to provide readers with an overview and background on the types of chemicals used in textile and leather goods manufacturing so that suppliers who make or finish textile and leather goods will have the necessary information to assess the likely environmental, workplace health, and consumer safety impacts of these products.