One Planet Business for Biodiversity (OP2B) is a unique international cross-sectorial, action-oriented business coalition on biodiversity with a specific focus on agriculture, initiated within French President Macron’s One Planet Lab framework, launched at the United Nations Climate Action Summit in New York on 23 September 2019. The coalition is determined to drive transformational systemic change and catalyze action to protect and restore cultivated and natural biodiversity within the value chains, engage institutional and financial decision-makers, and develop and promote policy recommendations for the 2021 CBD COP15 framework.